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PetsOvernight
Im in! I didnt know this exists until now. I think i will do good th it because i leave my computer on for 12+ hours a day, and i am oly playing games for 2 hours and doin internet things like gtaforums or IM'ing for an hour or so . Since I have a 2.4 gz'er, i tink i can contribute a lot.

When will my name be ion the list? I have 5 wu done already.

If you put your team number 32093, then once you complete one WU, you're name will be there. Nice work. :p

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Hey, mike39, i have one problem with folding.  After running DNETC a few hours my system likes to just die, and i look and the cpu temp is about 156 f.  that does not please me.

 

any advice?

Yeah, that's way too high and way too dangerous.  You, technically, should be okay until you get to 70* or 80*, but you're definitely pushing it to the limits.  I'll assume you, A) Don't have adequate cooling and B) Are running an AMD processor.  

 

First things first, you need to cut down on how much usage you let F@H take ahold of your processor.  You can modify this in your settings for F@H.  Then, if your temperatures don't drop - I'd recommend you stop the use of the F@H Client.  Folding is important, but making sure your processer doesn't die is more important.  If you're really adamant, then run out and buy some more casefans and perhaps a new, more efficient heatsink - but that's a bit of work just to keep folding.

 

:)  Hope that helps.

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Stank Hippie

FYI

 

A protein is basically a long chain polypeptide - poly meaning many, and peptide refering to the peptide/amide bond formed between the NH and carbonyl groups on the chain, making up a long string of amino acids.  The important part is that each amino acid can have a different side molecule attached to it - giving every amino acid in the chain different chemical properties.  These properties can be charge, polarity, affinity for certain atoms, etc....

 

Now, here is where the "folding" comes in.

 

A single polypeptide can be composed of millions of amino acids, and they are all in a linear form - much like a string.  The specific order of the chain is its primary structure.  When the chain begins to fold and twist upon itself, it can form things like sheets and helixes and is known as the secondary structure - your DNA is a double helix composed of long chains of nucleic acids.  When these sheets and helixes begin to fold and supercoil upon themselves, this finally forms the tertiary structure.  Now remember that this final, tertiary structure is composed of a SINGLE polypeptide chain, and is known as one subunit.  Almost done - when many different subunits interact they form proteins.  

 

Now you can only imagine the complexity of determining protein structure that is based on a mindbendingly large number of subunits, each of which is composed of a polypeptide chain containing MILLIONS of amino acids that are folding, and twisting, and writhing around to form a functional structure.

 

By participating in the protein folding program, you are basically using the processing power of your computer to assist with protein research.

 

More power to you.

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Exkabewbikadid
Now you can only imagine the complexity of determining protein structure that is based on a mindbendingly large number of subunits, each of which is composed of a polypeptide chain containing MILLIONS of amino acids that are folding, and twisting, and writhing around to form a functional structure.

 

By participating in the protein folding program, you are basically using the processing power of your computer to assist with protein research.

 

More power to you.

Well, thanks for that Mr. Scientist  :p

 

Yes, this is a very complex project to say the least.  I have read that one 400MHz processor would have to fold non-stop for 10,000 days (30 years) to simulate the folding of one protein, whereas dividing the work up amongst 30,000 processors would take 2 years to simulate the process.  This is the main reason the folding project was set up as a distributed computing effort rather than relying on supercomputers (which are only several hundred processors networked together).

 

So obviously, more processors dedicating idle clock cycles to folding will greatly speed up the time required to simulate the folding of a protien, which will allow science to move to the next steps in understanding why proteins misfold and cause illness.

 

The question I've been asking myself is whether or not this research will provide answers towards why certain cancers and diseases occur.  I certainly don't possess the biological and chemical knoledge to be making any educated guesses, but from what I've read on this project, I think the results are a very important step in the biomedical realm of science.  For one, this project goes hand in hand with the Human Genome Project which will be completed this year, which has already mapped the sequnce of human DNA.  AFAIK, cracking the human genome basically maps out the DNA code of protiens.  Although, the HG Project has raised a lot of concerns as to how the information can and should be used.  For example, with these results it is now possible to determine what health conditions an individual will face later in life.  This could result in insurance companies pre-emptively denying coverage to an individual just by being able to see into the future of that individual's health, something that is not ethical.

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You make it sound like a game but the point is to fight cancer not move up some league table. Isn't it enough that we are all doing our best? (minus the thousands of other members who have failed to fold...)

 

i think im gonna dissagree with you slightly there. I think that treating this as a game and making it a compition is not only good but also needed for the folding to work. As a majority we are competitive in nature, in everything we do. we always wanna be better then the next guy. People on these forums (especially noobs and spammers) are great examples. They are so aggresive that they compete in dumb things like post counts! With folding, if you can use those super-competitve people and get them to fold, they'll do their best to get as high on that list as they can. More then likely that what care about why they're doing it but they'll still do it. If they dont care about folding proteins to find the cure for CANCER but still do it, does it really matter if they care?

 

I think the best way to go about this is to make it a game. Start off as just a game for these forums because it'll take alot to touch the big guns (HardOCP, GenMay, etc...). And even if the gta team stays out of the top 100 for ever, dont get bumbed and stop folding. The program takes up no resources when you need them (minus some games) so if it's doing no harm why get rid of it?

[/rant]

 

i want to point out something to the people who run these forums. HardOCP.com has a complete site dedicated to folding and the site's owner (Mike McHugh) is the top folder in that team. The site backs the project and they have become extremly succesful. If we want this to go anywhere it's gonna need some support from the people that run these forums. And if you dont think it should get support, why? It's not like this is going to hurt anything. all it can do is help. there is no reason to bump this off and not help it get on it's feet.

 

sidenote: #7!!! woOt!

 

Edit: I just took a look at the HardOCP front page and the first post made by kyle is about folding. thats support right there... ohh and THE NEW CORE IS HERE!!!!!! hehe someone likes the matrix :D

 

 

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Exkabewbikadid
heeeey who bribed jevon :p

 

yes we're happy ;)

Nah, we didn't have to bribe anyone...

 

Let this be a lesson to all you kids out there:  If something doesn't go your way, just b*tch, whine, scream, throw endless tantrums, regress to name calling, threaten homocide, genocide and suicide, burn flags and revolt in the most irrational fashion you can think of untill your dreams come true!  :p

 

Seriously though, the majority disagreed with the administration and the administration was willing to listen to the majority.  Thanks for listening administration, we appreciate it.

[/off topic]

 

 

Anyways,  I'll probably be a way from folding (and the forums) for a few days.  I'm going to be building a new pc and I have to tear this one down in the process so I can free up this case.  But hopefully my new machine will "fold" circles around this one.

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heeeey who bribed jevon :p

 

yes we're happy ;)

Nah, we didn't have to bribe anyone...

 

Let this be a lesson to all you kids out there:  If something doesn't go your way, just b*tch, whine, scream, throw endless tantrums, regress to name calling, threaten homocide, genocide and suicide, burn flags and revolt in the most irrational fashion you can think of untill your dreams come true!  :p

 

Seriously though, the majority disagreed with the administration and the administration was willing to listen to the majority.  Thanks for listening administration, we appreciate it.

[/off topic]

 

 

Anyways,  I'll probably be a way from folding (and the forums) for a few days.  I'm going to be building a new pc and I have to tear this one down in the process so I can free up this case.  But hopefully my new machine will "fold" circles around this one.

Actually, I'm pretty sure it's because Tank said he would rape Jevon if he didn't...

 

:O

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ok i havent been folding for a few 3-4 days due to trouble with hard drive(s)

 

now i'm semi-back, and i just reached 3k :D

offline for 4 days and your still at the top.... man i have 5 computers running this program and I'm struggling to get top 5! thats just not fair.... wanna give me half of your dually

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Exkabewbikadid

Team Rank:  300  Wohoo!

 

Another 200 places and we'll be to the top 100, but that's not gonna happen anytime soon unless we increase the amount of processors ten fold.  But keep on folding everyone.  Maybe we'll pick up more processors in the next few weeks/months and reach the top 100.

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Weeeeee! We're in the top 300!  Are climbage through the ranks has slowed to a crawl, however...  :/  

 

I know we can do a lot better than this...we only have 60 people folding in a forums of over 30,000!  C'mon guys!  I have mine using 100% CPU and it hardly affects anything...and I dont know if this has been said, but is there anyway to always do the /1600 WU's???  I got 2 before and I can do em pretty fast, but my last 10 or so WU's have been wimpy 400's  :angry:

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is there anyway to always do the /1600 WU's???

I'd love to find a way to make sure faster PCs get big WUs, and slower ones get small ones. My PII-350 only just finished a nearly-month-long crunching period for a single 70point WU, while my P4-2.7 has run through a few of them in under a week. The multiple huge WUs within days have really boosted my score.

 

 

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Exkabewbikadid
Can anyone link me to some kind of folding manager that could turn the program on and off at specific intervals? I ask this because f@h heats up my cpu wayyy too much, and I dont want to forget its on and burn up my cpu.

If your processor is overheating, then right click on the icon in the system tray (by the clock) and select configure > andvanced > and slide the CPU percent usage down from 100%.

 

What's you CPU temp?  You might want to check that your cooling is ok in your case.  The f@h program shouldn't be heating it to a dangerously high temperature.

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sup ppl I just started this and I have a couple questions. I also don't especially feel like reading through the 18 pages of this thread so my questions may have been answered so.. sorry  :/  

 

1) How do I do more than 1 work unit at a time?

 

2) I finished one work unit but I'm not listed on the site, does it take a really long ttime to update?

 

3) Is there any way to chose which work unit you want to work on or is it random. Also, is there any way to tell how many points a given work unit is worth? I'm doing one now that is 100 units big, my first one was 500 and was worth 33 points, so do I just have to do the math to figure out how much eash work unit is worth or is there an easier way?

 

Thanks.

 

 

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Thanks for joining the team!  :)

 

To answer your questions, only one computer can work on one WU.  So, you can download the program on all the computers you have, and just put down the same username, which is the only way to work on more than one WU.

 

I believe the site takes AT LEAST one hour to update, sometimes more.  If it hasn't updated in a day, then maybe you didn't actually complete a WU?  Make sure to refresh the page, and check the F@H log file.  (Right click it in the system tray, goto Status>Log File)  It should say if it completed the WU or not.

 

For the final question, the WU's are random.  I prefer the 1600 ones since I can get them done just as fast as a 400 (doesn't really make sense), but they're obviously worth more points.  I've never heard of a 100 WU though.  If you're on a fairly slow computer I think you can change it to get certain kinds of WU's, but someone else would hafta tell you how to do that.

 

Good luck and thanks for folding!

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There are 100-Frame WU's, knightmare - I used to get them a lot back in January or so.  Anyway, there *is* a way to choose what core your WU is, but I'm not sure which.  There's the Gromac and Tinker core.  There's a way to choose which is which, but it requires you to do a bit of work - and I've found that only the super-hardcore guys need to change it.  The increment in points you get is small.

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cool thanks for the reply. I just took a look at my log file and the work unit supposedly finnished at 11:54 this morning which is about 5 hours ago, so the page must be slow refreshing.

 

my comp is average I would say, maybe a bit on the slow side; I have an AMD athalon 1.4, but the work units go so f*ckin slow! I also don't notice any real slowdown when I play games, even when I have F@H set at 100%.. I wonder why...

 

Anyway thanks for your help, ima get crack-a-lackin on these proteins.

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Exkabewbikadid
Anyway, there *is* a way to choose what core your WU is, but I'm not sure which.  There's the Gromac and Tinker core.  There's a way to choose which is which, but it requires you to do a bit of work - and I've found that only the super-hardcore guys need to change it.  The increment in points you get is small.

Do you mean choose between Tinker and Gromacs?

 

Getting Gromacs cores 99% of the time is easy.  You just add -advmethods to the target lines in all the shortcuts that you execute f@h from.  Shut down f@h and re-execute it with the new -advmetheds tag.

 

And yeah, Gromacs core is a much more efficient code than Tinker core, especially on Pentiums.  If it wasn't for -advmethods, there is no way in hell my 1.8 P4 would have over 2,000 points right now :p  AMD athlons fold Tinkers much better than Pentiums, so -advmethods isn't much more efficient, but it can still help some.

 

So I reccomend everyone, esppecially with a Pentium, use the -advmethods to get Gromacs.  It's my understanding that Stanford U plans to phase out Tinker anyways.

 

If anyone needs instructions for adding the -advmethods tag, just ask.  I've written out the instructions, but they are buried in this 18 page mess.  Maybe I'll ask mike39 to edit them into his first post.

 

Edit:  Oh yeah, my Hyper-threading P4 3.0C is up and running.  I just got to set up a network and...  :devil:

 

 

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I've got a 2.26 P4, care to explain again how to get Gromacs?  :colgate:

 

Getting Gromacs cores 99% of the time is easy.  You just add -advmethods to the target lines in all the shortcuts that you execute f@h from.  Shut down f@h and re-execute it with the new -advmetheds tag.

 

What he said. I don't really care, as I've been getting loads of 638s and 639s, which are HUGE in terms of points, yet take mere hours for my P4-1.8A @ 2.7 to do. I'm trying it anyway.

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