Solo players are easy to victimize in this game
Not always lol. Obviously you need a little common sense - if there's a group of tryhards on your back then you don't burden yourself with having to protect a cargo sale. You get your sales done early, or in other sessions where you haven't alienated anyone.
Without cargo to protect, a solo player is a lot harder to victimize. The odds will be against me if there's a group of tryhards, but they regularly get outsmarted. They're predictable.
tryhards have no friends.
Also not always true. I often see them in packs.
Overall, some cargo things aren't viable in a public session. Biker business cargo and old crate cargo - both can be locked onto by missiles, making them vulnerable even to the meme-mobiles. Plus with crates, the stakes get way too high. For those, I use empty sessions.
Bunker cargo - I've made a lot off that solo. Just buy supplies; once they're used up start a sale. Have a little initiative. Don't start a sale just after you've p*ssed someone off - or if you p*ssed off anyone in that session at some point. If there's a jet flying around killing everyone, it's safest to find another session (you could take him down, but then you'll hurt his ego and he'll try destroy your cargo). Or a barcode sitting in his facility - these kind of things mean a session isn't a good place to sell.
Vehicle cargo - same as above.
The stuff I follow is really stuff a group of players would have to follow too. Unless you had about 20 people guarding you, then you don't want to sell in a session you've made enemies in. All it takes is one orbital strike, one deviously-placed proximity mine, one Akula, or one off radar guy in a jet who doesn't mind if he goes down with his jet (all he has to do is rush in and destroy a slow cargo vehicle; doesn't matter if he's taken down afterwards, the damage is done).
TL;DR: Lay low, keep your head down, use some common sense. If the cargo matters to you and you can't afford to lose it, then do it solo, since it's impossible to 100% ensure the safety of cargo - unless at least half the session is friends with you. Even then - technically all it takes is for one guy to have had a devious enough mind to put a proxy at a delivery point, that kind of thing.
I guess I’m just not that worried about the money. I suppose, in a way, we’re really using the sale to generate some action. If some cargo gets destroyed, it ain’t gonna kill me. And, in fact, it has happened. It’s part of the game. I only do the bunker and the coke, and only purchase supplies, so I have no sweat equity in the cargo. Since I don't do any actual grinding, maybe it’s easier for me to let go of it? If people are so worried about losing cargo all the time, maybe they’d be better off making money with Heists? There, you only have to deal with the NPCs, which is way easier than actual humans who, as you note, can be very devious.
I’m generalizing a bit, of course, about solo player and tryhards. But more often than not, griefers and tryhards are solo players, and for that reason, easy for a crew to deal with. These types are usually looking for easy targets, and they often leave the lobby once they realize what they’re up against.
People can do things the way they want, of course. But, based on the complaints I hear, over and over, people are not enjoying it. I’m trying to offer a way that I think is a lot more fun. Believe me, I’ve done stuff in empty lobbies, too. I found it to be boring, and I thought it was kinda cowardly. We’ve done it sort of the opposite way, too - grief almost everyone out of a lobby, then do the sale. But I think it’s a lot more fun and exciting the way I outlined. And if you have that many people, why be afraid? It took me a while to convince my friends to try it like this, but once they did, they all loved it.