So a big complaint from many is the big focus on the corrupt government in GTA V and I overall agree (just too many missions revolving around the FIB and their conflict with the IAA, I think Merryweater was even worse though).
But which other organizations should they have used? LC had the Italian mafia and we know it has a big presence in NY (even if they aren't as important as they used to be). Then there was also a good amount of focus on the Russian mob. Both fitted very well.
There was the Madrazzo cartel in V which had the potential to take over a similiar role and was wasted completely. But are cartels even that prominent in Los Angeles (like the mob is in NY).
Using the Ballas too much would make it feel like GTA SA and only really affect Franklin