I watched it a little more and read into some plot points. Apparently, there's three different metamorphic xenos, and we probably won't see the original until the end. I read that the other xenos are called neo-morphs? Not sure if that rumor is true.
But after watching the trailer again, I'm going to take a guess and say Shaw and David reached the engineer's home planet, but crash landed. I assuming Shaw died, but David remains, waiting. I say this because the credits now have Fassbender playing two androids, both David and Walter. So I think the new crew is on a rescue mission, and the Derelict spaceship we see is Shaw's. It can't be the Derelict from Alien, because LV426 had a different landscape. I wonder if David had been waiting all this time to see his sinister plans unfold. I think the irony there is that plays into the narrative of our creations turning on us like we did to the engineers.