It seems these days that GTA fans have a bad case of nostalgia. IV was slammed because it wasn't San Andreas 2.0 and V gets slammed because it is not IV on the west coast and I think a big part of this is this that they take place in locations R has done before. I think their recreations of New York and LA or both great but maybe it is time for R to move the franchise to somewhere it has never been before. If they do Vice City for VI people will just compare it to the PS2 game and criticize it like they do with V and San Andreas. The same thing will happen if they do Venturas or San Fierro
If they do a new location like a game based on The South or a game based on 1970s Chicago and Detroit I people for the most part will judge them on their own merits because it would be starting fresh and it will send the message that the series truly is moving forward. It will also help creativity at R because it will be a fresh start.