A life simulator never. What I will think it will turn into is a culture simulator. We already see the roots of this in GTAV.
What you see with internet browsing, the trash tv, the internet dating, it's all part of our culture now.
I don't believe Rockstar's ideal of simulating the world outside is ever going to be about replicating pissing and sh*tting and forcing you to eat every six hours. It's going to be about culture. Thirty years time, we'll all be online and when they do achieve their goal, my money is online will be the basis of it.
The first thing to go will be radio stations - at least, radio stations as we know them. No longer will they play a set list. They will be streamed directly through our consoles and change up weekly, reflecting the current hits. There may be one or two presets for older music, but nothing like there is now. News reports will parody the current affairs of the time; hell, even the weather may reflect what's going on outside. Hurricanes, for instance. Pedestrians will be updated periodically, introducing the fashions of the time, the way people interact and talk to each other. Think Google Glasses and how people chat away on those bluetooth headsets. This is no new concept: Miami Vice used to do the same thing when it ran twenty five years ago. You can see why Vice City was the way it was, so engrained in the culture of the 1980s.
The biggest feature they will attempt to capture are the changing landscapes. Billboarding and advertising will change. Construction will slowly take place on new buildings - the old will be demolished. Seasons will dump snow all over the skyline, cast the rivers in ice. They will have all of this to contend with in regular updates to keep the game fresh.
Where will this leave the GTA of old, the games set in the past? Long gone. I don't think we will ever see a GTA game with the balance leaning towards crime over culture again, at least not like San Andreas or GTAIV. Not unless they set the game in eras where crime was such a part of culture it was impossible to ignore (think New York in the 70s and 80s; what SA did with Los Angeles of the early 90s) will we see that focus, sadly. And this is why I think a GTA game set in the 70s has a good chance of coming up next. There's both enough parody fodder in the culture and enough crime to strike the perfect balance. They'll do it once and move on.
Come back to this post in 2044.