These three would be the core of a circus that moves about the west.
The circus would be mere sideshow for daring bank heists the trio would be doing in those towns the circus were in at any given time. Heists in GTA style!
This would be creative and new.
Sadly, Rockstar dev team is not known for creativity, so it is likely the new protagonist will be some boring dude with chip on his shoulder, as usual for these boring Rockstar games...