There NEEDS to be a northern city that has a snowy climate. Vice City is great, but it isn't that different from Los Santos's tropical climate. Other than street layout, and name, it's STILL palm trees, condominiums, skyscrapers, beaches and bright lights.
I'm all for it, but it HAS to include a large northern city that is snowy and cold. If it's only southern Florida, I can GUARANTEE people will go apesh*t because they will say it feels almost exactly like GTAV. Furthermore, the attachment to Vice City has as much, if not MORE to do, with the 80's/scarface vibe that made that game so great.
Many people will be disappointed when it's a modern day setting with a better looking, but unrecognizable Vice City.
I'm not saying it won't be a great game, but it's not going to be what people think it's going to be.