We don't even know if those ARE transsexuals/transgendered persons..
They could just be males in drag, in which case, many drag queens look exactly like that.
Edit: Aight I looked it up and they actually are transgendered people.
Still doesn't matter since all GTA characters are parodies of the worst aspects of a group's stereotypical behaviors. Everything bad a Republican has ever said about a Democrat is exactly what the Democrats are in the game, and vice-versa. Transgendered people aren't exempt..
Look at Jimmy. He's a 20 something year old rich obese white kid, with no job, doesn't go to school, smokes, drinks, plays Call of Duty all day and trolls people on the internet for fun.
It's kinda funny how when it's "strippers","feminists", "hookers" and "transgendered people" it's unacceptable hate, but when it comes to making fun of "self-entitled lazy gamers", "politicians", "celebrities", "rednecks", "corrupt police" it's hilarious satire.
Why are some targets acceptable and others aren't?
Oh right, because "equality". "We're equal, so we have the right not to be made fun of in a game that makes fun of everybody."
I understand completely.