If we're talking this decade then as of now The Elder Scrolls series does have an adventage of the GTA seires considering there hasn't been a GTA entry this decade until next week, so by default yes Skyrim has it. With this said, silly polls aside it's apples and oranges to compare the two, and what a lot of you fail to realize is that it is perfectly possible to like both games without having to resort to calling one particular title sh*t.
I'm fairly sure I've said this in another topic comparing both of these series but both titles do set out to achieve different things, one is rooted in our world and provides a somewhat skewed view on how people live modern life, it draws inspiration from television and film to craft its story and aims to put us at the heart of the action. The other is a sprawing fantasy tale which creates an entirely new world drawing from the likes of Tolkien and such to put players into this world of magic, dungeons, dragons and so much more. Both can very easily co-exist and I know the two sets of developers have an immense respect for one another.
As far as my own personal tastes go, I don't think anything can really displace GTA Vice City as one of if not my favourite game of all time, with GTA San Andreas coming fairly close. I would however sit Oblivion right up there next to Vice City. Oblivion was my first title on the Xbox 360, it was my first proper Elder Scrolls title, I still remember that sense of awe as the environment changed when you approach an Oblivion gate, that was a defining moment of this generation. I would probably rank it above GTA3 and GTA4 as far as favourites go.
I don't know where I would put Skyrim in this equation though, I sank a lot of hours into Skyrim but something about it just didn't click with me the same way Oblivion did. I suppose it might be the same feeling people got moving from Morrowind into Oblivion. WIlling to give it another try some day though.
For sheer impact and importance to me I'd probably go with the GTA series, but Elder Scrolls isn't that far behind, they are both wonderful titles and gamers are really lucky to have so much choice on offer.