I'd be in favour of london, it would be better than places such as tokyo or brazil, problem with those places would be culture, I can't see what R* would do with things like talk radio, ped lines, pop culture references, news, paradies if gta was set in eg Moscow, it would prob go over most peoples heads or just come across as overly rascist or too sterotypical, gta has always been subtle with certain things.
I would argue they should set it in the 60's again, it would be prime and I think was a major cultural point for england and britishness, similar to how the 80's were a major part of making vice city so memrable and unique.
pleanty of things to reference too, beatles, the queen, troubles in Northern Ireland, collapse of the empire, the war and Germans
close link to America, so pleanty of references there plus it would allow pleanty of american music on the radio, the cold war would be another source ripe for parody, iconic british cars that were actually made in britain, jaguar e tpe, mini cooper, astin martin DB5, list goes on. london is a large melting pot like america, with people from all over the common wealth living there and a variety of diff gangs ranging from yardies to classic britsh gangsters.
Plus R* north are based in scotland, so they would be able to pull of a british gta game perfectly.
This is why im against other cities such as paris and tokyo, anyone who wants these cities please list of things they could parody like I've mentioned above, such as cars, politcics, culture music etc.
P.s the oh left handed traffic is a bs arguement, we drive on the left here in the REP. and I have never once had trouble adpting to the right handed traffic in gta, or had trouble re adapting to the left when i go out to drive IRL after plain gta. so better excuses please.