- Liberty City Commission a.k.a. The Five Families (Cosa Nostra)
- Alderney Mob (Cosa Nostra)
- Albanian Mob
- Russian Organized Crime Syndicate
- Irish Mob
- Liberty City Triads Organization
- Spanish Lords
- Jamacian/West-Indian Criminal Gangs
- Firefly Projects Gang
- North Holland Hustlers
- Angels of Death M.C.
- The Lost M.C.
- Korean Mob
- Leftwood Hispanic Street Gang
Liberty City Cosa Nostra
(Messina, Provano, Gambetti, Lupisella and Ancelotti crime families)
Located in Little Italy.
Take a more subtle approach when it comes to their "uniforms". Members are sometimes hard to identify as they look more like normal civilians than gangsters.
- Alderney Mob
(Pegorino crime family)
Headed up by Jimmy Pegorino.
Notable members: Phil Bell, Ray Boccino.
Quite small-time compared to other mobs around the city. The Albanians have no real pull or power in Liberty City besides a few missions, members are hard to identify and are sometimes confused as Russians.
Russian Organized Crime Syndicate
(Faustin and Petrovic crews)
Run Hove Beach.
Much alike the Cosa Nostra in terms of the way they appear to the player.
Kenny Petrovic is hinted at as being the boss of not only Liberty City's Russian crime syndicate but the whole country's.
Notable members: Mikhail Faustin, Dimitri Rascalov, Kenny Petrovic.
(McReary crime family)
Once use to be the biggest crime family in Liberty City, now are on the decline thanks to the mafia and waves of Russian/Eastern-European immigrants. Hang in Steinway.
Notable members: The McReary family.
Liberty City Triads Organization
Not much is known about them this time 'round, they hang in Chinatown.
Based off real street gang, the Latin Kings.
Hang out in South Bohan.
Members can be identified by their black and gold bead necklaces aswell as pre-dominately yellow and black/white clothing.
Former gang of reformed "gangsta", Manny Escuela.
Jamacian/West-Indian Criminal Gangs
Warring crews set this gang as a bit more complicated than the others. Their name is never revealed but they could be labelled as "Yardies".
Hang in Beechwood City.
Notable members: Jacob "Little Jacob" Hughes, Real Badman.
Firefly Projects Gang
African-American street gang that seem to be based off of the Bloods.
Sport black/white and primarily red.
So small they're not even on the map. Came across some who'd look like they'd been on smack. Very aggressive, seem to fester mainly in Algonquin.
Leftwood Hispanic Street Gang
Could be the rivals of the Spanish Lords.
Sport purple and black bead necklaces but dress in the same manner as the Spanish Lords.
North Holland Hustlers
Unlike the other street gangs in the game, they're usually a bit harder to identify because they don't sport particular colors. They are Dwayne Forge's gang.
The Lost Motorcycle Club
Angels of Death Motorcycle Club