So I'm only using some basic mods, alongside Things To Do, and have had no issues so far. However for some reason when I try to start the Trucking side-mission, it softlocks. The "Trucking" yellow mission text appears in the bottom right and the screen goes black, then it just stays that way. I can pause the game, and if I unpause I hear traffic and such, but I have no control and have to restart the game. I'll list my mods below.
Wesser Widescreen Fix
Pretty much all of these only effect either some minor graphical things, however I'm not sure if SilentPatch or possibly even Ginput could be causing the issue? I'm not sure.
Of course, none of those mods can affect your game in that way. Possibly, your save file is glitched.
Well bugger! Thanks for letting me know at least, I think I'll just chill and keep playing (was hoping to 100%) and when 2.0 is eventually finished and put out I'll just start fresh.